- CM Punk defeated The Miz, Chris Jericho, Kofi Kingston, Dolph Ziggler (with Vickie Guerrero), and R-Truth in an Elimination Chamber Match to retain the WWE Championship.
- Beth Phoenix defeated Tamina Snuka to retain the Divas Championship.
- Daniel Bryan defeated Santino Marella, Wade Barrett, Cody Rhodes, Big Show, and The Great Khali in an Elimination Chamber Match to retain the World Heavyweight Championship.
- Jack Swagger (with Vickie Guerrero) defeated Justin Gabriel (with Hornswoggle) to retain the United States Championship.
Main Event Edit
John Cena defeated Kane in an Ambulance Match.