She debuted on July 24, 1987, defeating The Fabulous Moolah for the WWF Women's Championship. Renaming herself Sensational Sherri, she reigned as WWF Women's Champion for fifteen months before losing it to Rockin' Robin. At the Survivor Series in 1987, Martel's team consisting of Martel, The Glamour Girls (Leilani Kai and Judy Martin), Dawn Marie, and Donna Christanello lost to The Fabulous Moolah's team consisting of Moolah, Velvet McIntyre, Rockin' Robin, and the Jumping Bomb Angels (Noriyo Tateno and Itsuki Yamazaki). It was on October 8, 1988 that she was defeated for the title by Rockin' Robin. When the WWF phased out its women's division in 1990, Martel remained with the company and turned her attention to managing male wrestlers.
During the late 1980s Sherri often donned a blonde wig and sunglasses and played the role of then WWE Intercontinental Champion the Honky Tonk Man's girlfriend "Peggy Sue" and accompanied Honky and his manager "The Mouth of the South" Jimmy Hart to the ring for his matches, including his match with Brutus "The Barber" Beefcake at WrestleMania IV.
At WrestleMania V, Martel confronted Miss Elizabeth, which led to a brawl between Elizabeth's ally Hulk Hogan and her former ally Randy Savage. Throughout the remainder of 1989, Martel and Savage feuded with Hogan and Elizabeth. At SummerSlam, Hogan and Brutus "The Barber" Beefcake defeated the team of Savage and Zeus. After the match, Elizabeth knocked out Martel with Martel's purse, and she, Hogan, and Beefcake cut Martel's hair.
At WrestleMania VI in 1990, Martel and Savage lost a mixed tag-team match against Sapphire and Dusty Rhodes after Elizabeth, who was in the corner of Sapphire and Rhodes, interfered and shoved Martel. During that same year, Martel and Savage appeared on Lifestyles of the Rich and Famous with Robin Leach. Martel ran in the ring to aid Savage in a steel cage match in Memphis against Jerry "The King" Lawler, but after accidentally knocking Savage from the ring, she had her dress yanked off by Lawler as she climbed the cage to escape. During a steel cage match at Madison Square Garden, Martel would suffer a similar embarrassment at the hands of The Ultimate Warrior, who pulled off an escaping Martel's miniskirt to reveal matching black garter belts and lace underpants. Practically in tears, Martel raced back to the locker room. At WrestleMania VII, Savage lost a "retirement match" against The Ultimate Warrior, where the loser would be forced (Kayfabe) to retire. After Savage lost the match, an irate Martel attacked Savage but was thrown from the ring by Elizabeth, who had been watching from the audience. Later on the WM7 card after she and Savage parted ways following the career match, Martel came to the ring to help "The Million Dollar Man" Ted DiBiase in his assault on an injured Rowdy Roddy Piper, following which she managed DiBiase until 1992.
Subsequently, Martel began managing Shawn Michaels after Pat Patterson convinced Michaels to participate in the storyline. She also sang Michaels theme song called "Sexy Boy". As part of his gimmick, Michaels would admire himself in a full-length mirror before his matches. In 1992, before a match, his former partner Marty Jannetty grabbed the mirror and attempted to hit Michaels with it, but Michaels pulled Martel in front of him. After being hit with the mirror, she was absent from television until the Royal Rumble in January 1993. At the Rumble, she was in a neutral corner for the match between Michaels and Jannetty, but she turned on Michaels during the match. Backstage, Michaels confronted her, and Jannetty came to her rescue. The storyline, however, was cut short as Jannetty was released from the company in the midst of the feud. Martel spent the remainder of the year aligned with Tatanka, who aided her in her feud with Luna Vachon and Bam Bam Bigelow. She was released from the World Wrestling Federation during the summer.
In 2005, she took part in a World Wrestling Entertainment (formerly the WWF) storyline with Shawn Michaels and Kurt Angle shortly before WrestleMania 21. She made a return to SmackDown!, singing a parody of Michaels's theme song with Angle.
She was inducted into the WWE Hall of Fame by Ted DiBiase in April 2006.
She died on June 15, 2007.